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Denervation during mandibular distraction osteogenesis results in impaired bone formation
Mandibular distraction osteogenesis (DO) is mediated by skeletal stem cells (SSCs) in mice, which enact bone regeneration via neural crest re-activation. As peripheral nerves are essential to progenitor function during development and in response to injury, we questioned if denervation impairs mandi...
Autores principales: | Tevlin, Ruth, Griffin, Michelle, Chen, Kellen, Januszyk, Michael, Guardino, Nick, Spielman, Amanda, Walters, Shannon, Gold, Garry Evan, Chan, Charles K. F., Gurtner, Geoffrey C., Wan, Derrick C., Longaker, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902545/ https://www.ncbi.nlm.nih.gov/pubmed/36747028 http://dx.doi.org/10.1038/s41598-023-27921-9 |
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