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High-throughput single-molecule quantification of individual base stacking energies in nucleic acids

Base stacking interactions between adjacent bases in DNA and RNA are important for many biological processes and in biotechnology applications. Previous work has estimated stacking energies between pairs of bases, but contributions of individual bases has remained unknown. Here, we use a Centrifuge...

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Detalles Bibliográficos
Autores principales: Abraham Punnoose, Jibin, Thomas, Kevin J., Chandrasekaran, Arun Richard, Vilcapoma, Javier, Hayden, Andrew, Kilpatrick, Kacey, Vangaveti, Sweta, Chen, Alan, Banco, Thomas, Halvorsen, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902561/
https://www.ncbi.nlm.nih.gov/pubmed/36746949
http://dx.doi.org/10.1038/s41467-023-36373-8