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Rational design of enzyme activity and enantioselectivity

The strategy of rational design to engineer enzymes is to predict the potential mutants based on the understanding of the relationships between protein structure and function, and subsequently introduce the mutations using the site-directed mutagenesis. Rational design methods are universal, relativ...

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Detalles Bibliográficos
Autores principales: Song, Zhongdi, Zhang, Qunfeng, Wu, Wenhui, Pu, Zhongji, Yu, Haoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902596/
https://www.ncbi.nlm.nih.gov/pubmed/36761300
http://dx.doi.org/10.3389/fbioe.2023.1129149