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Application of neural network-based image analysis to detect sister chromatid cohesion defects

Sister chromatid cohesion (SCC) is mediated by the cohesin complex and its regulatory proteins. To evaluate the involvement of a protein in cohesin regulation, preparations of metaphase chromosome spreads and classifications of chromosome shapes after depletion of the target protein are commonly emp...

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Detalles Bibliográficos
Autores principales: Ikemoto, Daiki, Taniguchi, Tomoya, Hirota, Kouji, Nishikawa, Kiyoshi, Okubo, Kan, Abe, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902603/
https://www.ncbi.nlm.nih.gov/pubmed/36747022
http://dx.doi.org/10.1038/s41598-023-28742-6