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Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer

BACKGROUND: Naturally occurring germline gene deletions (KO) represent a unique setting to interrogate gene functions. Complete deletions and differential expression of the human glycosyltransferase UGT2B17 and UGT2B28 genes are linked to prostate cancer (PCa) risk and progression, leukaemia, autoim...

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Detalles Bibliográficos
Autores principales: Rouleau, Michèle, Nguyen Van Long, Flora, Turcotte, Véronique, Caron, Patrick, Lacombe, Louis, Aprikian, Armen, Saad, Fred, Carmel, Michel, Chevalier, Simone, Lévesque, Eric, Guillemette, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902621/
https://www.ncbi.nlm.nih.gov/pubmed/36347965
http://dx.doi.org/10.1038/s41416-022-02040-w