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Implications of S-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis

The discovery that cardiac sarcomere proteins are substrates for S-glutathionylation and that this post-translational modification correlates strongly with diastolic dysfunction led to new concepts regarding how levels of oxidative stress affect the heartbeat. Major sarcomere proteins for which ther...

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Detalles Bibliográficos
Autores principales: Rosas, Paola C., Solaro, R. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902711/
https://www.ncbi.nlm.nih.gov/pubmed/36762302
http://dx.doi.org/10.3389/fcvm.2022.1060716