GPR52 regulates cAMP in T cells but is dispensable for encephalitogenic responses

G-protein coupled receptors (GPCR) regulate 3’,5’-cyclic adenosine monophosphate (cAMP) levels in T cells. cAMP as ubiquitous second messenger is crucial for adequate physiology of T cells by mediating effector T cell (Teff) function as well as regulatory T cell (Treg)-mediated immunosuppression. Se...

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Detalles Bibliográficos
Autores principales: Krieg, Paula F., Sonner, Jana K., Kurelic, Roberta, Engler, Jan Broder, Scharenberg, Marlena F., Bauer, Simone, Nikolaev, Viacheslav O., Friese, Manuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902724/
https://www.ncbi.nlm.nih.gov/pubmed/36761164
http://dx.doi.org/10.3389/fimmu.2022.1113348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902724/
https://www.ncbi.nlm.nih.gov/pubmed/36761164
http://dx.doi.org/10.3389/fimmu.2022.1113348

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