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GPR52 regulates cAMP in T cells but is dispensable for encephalitogenic responses
G-protein coupled receptors (GPCR) regulate 3’,5’-cyclic adenosine monophosphate (cAMP) levels in T cells. cAMP as ubiquitous second messenger is crucial for adequate physiology of T cells by mediating effector T cell (Teff) function as well as regulatory T cell (Treg)-mediated immunosuppression. Se...
Autores principales: | Krieg, Paula F., Sonner, Jana K., Kurelic, Roberta, Engler, Jan Broder, Scharenberg, Marlena F., Bauer, Simone, Nikolaev, Viacheslav O., Friese, Manuel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902724/ https://www.ncbi.nlm.nih.gov/pubmed/36761164 http://dx.doi.org/10.3389/fimmu.2022.1113348 |
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