Enhancement of adenosine A(2A) signaling improves dopamine D(2) receptor antagonist-induced dyskinesia via β-arrestin signaling

Repeated administration of dopamine D(2) receptor (D2R) antagonists, which is the treatment for psychosis, often causes tardive dyskinesia (TD). Despite notable clinical demand, effective treatment for TD has not been established yet. The neural mechanism involving the hyperinhibition of indirect pa...

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Detalles Bibliográficos
Autores principales: Nagaoka, Koki, Asaoka, Nozomi, Nagayasu, Kazuki, Shirakawa, Hisashi, Kaneko, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902764/
https://www.ncbi.nlm.nih.gov/pubmed/36760795
http://dx.doi.org/10.3389/fnins.2022.1082375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902764/
https://www.ncbi.nlm.nih.gov/pubmed/36760795
http://dx.doi.org/10.3389/fnins.2022.1082375

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