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A novel defined TLR3 agonist as an effective vaccine adjuvant

Synthetic double-stranded RNA analogs recognized by Toll-like receptor 3 (TLR3) are an attractive adjuvant candidate for vaccines, especially against intracellular pathogens or tumors, because of their ability to enhance T cell and antibody responses. Although poly(I:C) is a representative dsRNA wit...

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Detalles Bibliográficos
Autores principales: Ko, Kwang Hyun, Cha, Seung Bin, Lee, Seung-Hwan, Bae, Hyun Shik, Ham, Chul Soo, Lee, Min-Gyu, Kim, Dong-Ho, Han, Seung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902914/
https://www.ncbi.nlm.nih.gov/pubmed/36761735
http://dx.doi.org/10.3389/fimmu.2023.1075291