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Intravenous AAV9 administration results in safe and widespread distribution of transgene in the brain of mini-pig

Animal models are important for understanding the pathogenesis of human diseases and for developing and testing new drugs. Pigs have been widely used in the research on the cardiovascular, skin barrier, gastrointestinal, and central nervous systems as well as organ transplantation. Recently, pigs al...

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Detalles Bibliográficos
Autores principales: Lin, Yingqi, Li, Caijuan, Wang, Wei, Li, Jiawei, Huang, Chunhui, Zheng, Xiao, Liu, Zhaoming, Song, Xichen, Chen, Yizhi, Gao, Jiale, Wu, Jianhao, Wu, Jiaxi, Tu, Zhuchi, Lai, Liangxue, Li, Xiao-Jiang, Li, Shihua, Yan, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902950/
https://www.ncbi.nlm.nih.gov/pubmed/36762127
http://dx.doi.org/10.3389/fcell.2022.1115348