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Pan-cancer analysis of chromothripsis-related gene expression patterns indicates an association with tumor immune and therapeutic agent responses

Chromothripsis is a catastrophic event involving numerous chromosomal rearrangements in confined genomic regions of one or a few chromosomes, causing complex effects on cells via the extensive structural variation. The development of whole-genome sequencing (WGS) has promoted great progress in explo...

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Detalles Bibliográficos
Autores principales: Zhang, Qin, Yang, Lujie, Xiao, He, Dang, Zhaoqian, Kuang, Xunjie, Xiong, Yanli, Zhu, Jianwu, Huang, Zhou, Li, Mengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902954/
https://www.ncbi.nlm.nih.gov/pubmed/36761982
http://dx.doi.org/10.3389/fonc.2023.1074955