Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF‐1α

Tumour cells under hypoxia tend to modulate the number and contents of extracellular vesicles (EVs) to regulate the tumour microenvironment (TME) and thus promote tumour progression. However, the mechanism of how hypoxia influences the secretion of EVs remains to be elucidated. Here, we confirm the...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoning, Wu, Ruoyi, Zhai, Peisong, Liu, Zheqi, Xia, Ronghui, Zhang, Zhen, Qin, Xing, Li, Chuwen, Chen, Wantao, Li, Jiang, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903130/
https://www.ncbi.nlm.nih.gov/pubmed/36748335
http://dx.doi.org/10.1002/jev2.12310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903130/
https://www.ncbi.nlm.nih.gov/pubmed/36748335
http://dx.doi.org/10.1002/jev2.12310

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