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String/Cdc25 phosphatase is a suppressor of Tau-associated neurodegeneration

Tau pathology is defined by the intracellular accumulation of abnormally phosphorylated Tau (MAPT) and is prevalent in several neurodegenerative disorders. The identification of modulators of Tau abnormal phosphorylation and aggregation is key to understanding disease progression and developing targ...

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Detalles Bibliográficos
Autores principales: Oliveira, Andreia C., Santos, Madalena, Pinho, Mafalda, Lopes, Carla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903143/
https://www.ncbi.nlm.nih.gov/pubmed/36601903
http://dx.doi.org/10.1242/dmm.049693