Conditional Fragment Ion Probabilities Improve Database Searching for Nonmonoisotopic Precursors

[Image: see text] Stochastic, intensity-based precursor isolation can result in isotopically enriched fragment ions. This problem is exacerbated for large peptides and stable isotope labeling experiments using deuterium or (15)N. For stable isotope labeling experiments, incomplete and ubiquitous lab...

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Detalles Bibliográficos
Autores principales: O’Brien, Jonathon J., Gadzuk-Shea, Meagan, Seitzer, Phillip M., Rad, Ramin, McAllister, Fiona E., Schweppe, Devin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903324/
https://www.ncbi.nlm.nih.gov/pubmed/36414539
http://dx.doi.org/10.1021/acs.jproteome.2c00247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903324/
https://www.ncbi.nlm.nih.gov/pubmed/36414539
http://dx.doi.org/10.1021/acs.jproteome.2c00247

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