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Conditional Fragment Ion Probabilities Improve Database Searching for Nonmonoisotopic Precursors
[Image: see text] Stochastic, intensity-based precursor isolation can result in isotopically enriched fragment ions. This problem is exacerbated for large peptides and stable isotope labeling experiments using deuterium or (15)N. For stable isotope labeling experiments, incomplete and ubiquitous lab...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903324/ https://www.ncbi.nlm.nih.gov/pubmed/36414539 http://dx.doi.org/10.1021/acs.jproteome.2c00247 |