Cargando…
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score
BACKGROUND: The popular statistics-based Genome-wide association studies (GWAS) have provided deep insights into the field of complex disorder genetics. However, its clinical applicability to predict disease/trait outcomes remains unclear as statistical models are not designed to make predictions. T...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903430/ https://www.ncbi.nlm.nih.gov/pubmed/36750873 http://dx.doi.org/10.1186/s12967-023-03939-5 |