Hypoxia-associated circPRDM4 promotes immune escape via HIF-1α regulation of PD-L1 in hepatocellular carcinoma

BACKGROUND: Hypoxia is a hallmark of cancer, and is closely intertwined with tumor immune evasion. Circular RNAs (circRNAs) have been implicated in tumor response to immune checkpoint blockades. However, hypoxia-associated circRNAs that orchestrate the association between hypoxia and response to imm...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-Qiang, Zuo, Xue-Liang, Cai, Juan, Zhang, Yao, Han, Guo-Yong, Zhang, Long, Ding, Wen-Zhou, Wu, Jin-Dao, Wang, Xue-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903500/
https://www.ncbi.nlm.nih.gov/pubmed/36747292
http://dx.doi.org/10.1186/s40164-023-00378-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903500/
https://www.ncbi.nlm.nih.gov/pubmed/36747292
http://dx.doi.org/10.1186/s40164-023-00378-2

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