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Potential role of doravirine for the treatment of HIV-1-infected persons with transmitted drug resistance

BACKGROUND: Doravirine has a unique resistance profile but how this profile might increase its usefulness beyond first-line therapy in persons with susceptible viruses has not been well studied. We sought to determine scenarios in which doravirine would retain activity against isolates from ART-naïv...

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Detalles Bibliográficos
Autores principales: Rhee, Soo-Yon, Schapiro, Jonathan M., Saladini, Francesco, Zazzi, Maurizio, Khoo, Saye, Shafer, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903540/
https://www.ncbi.nlm.nih.gov/pubmed/36750835
http://dx.doi.org/10.1186/s12981-023-00503-5