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GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT
BACKGROUND: Clear cell renal cell carcinoma (ccRCC), with its hallmark phenotype of high cytosolic lipid content, is considered a metabolic cancer. Despite the implication of this lipid-rich phenotype in ccRCC tumorigenesis, the roles and regulators of de novo lipid synthesis (DNL) in ccRCC remain l...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903620/ https://www.ncbi.nlm.nih.gov/pubmed/36750850 http://dx.doi.org/10.1186/s13046-023-02607-2 |