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GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT

BACKGROUND: Clear cell renal cell carcinoma (ccRCC), with its hallmark phenotype of high cytosolic lipid content, is considered a metabolic cancer. Despite the implication of this lipid-rich phenotype in ccRCC tumorigenesis, the roles and regulators of de novo lipid synthesis (DNL) in ccRCC remain l...

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Detalles Bibliográficos
Autores principales: Nguyen, Tin Tin Manh, Nguyen, Thi Ha, Kim, Han Sun, Dao, Thien T. P., Moon, Yechan, Seo, Munjun, Kang, Sunmi, Mai, Van-Hieu, An, Yong Jin, Jung, Cho-Rok, Kim, Jin-Mo, Park, Sunghyouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903620/
https://www.ncbi.nlm.nih.gov/pubmed/36750850
http://dx.doi.org/10.1186/s13046-023-02607-2