Integration of multiple lineage measurements from the same cell reconstructs parallel tumor evolution

Organoid evolution models complemented with integrated single-cell sequencing technology provide a powerful platform to characterize intra-tumor heterogeneity (ITH) and tumor evolution. Here, we conduct a parallel evolution experiment to mimic the tumor evolution process by evolving a colon cancer o...

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Detalles Bibliográficos
Autores principales: Kester, Lennart, de Barbanson, Buys, Lyubimova, Anna, Chen, Li-Ting, van der Schrier, Valérie, Alemany, Anna, Mooijman, Dylan, Peterson-Maduro, Josi, Drost, Jarno, de Ridder, Jeroen, van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903660/
https://www.ncbi.nlm.nih.gov/pubmed/36778661
http://dx.doi.org/10.1016/j.xgen.2022.100096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903660/
https://www.ncbi.nlm.nih.gov/pubmed/36778661
http://dx.doi.org/10.1016/j.xgen.2022.100096

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