Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing

Single-cell DNA sequencing (scDNA-seq) methods are powerful tools for profiling mutations in cancer cells; however, most genomic regions sequenced in single cells are non-informative. To overcome this issue, we developed a multi-patient-targeted (MPT) scDNA-seq method. MPT involves first performing...

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Detalles Bibliográficos
Autores principales: Leighton, Jake, Hu, Min, Sei, Emi, Meric-Bernstam, Funda, Navin, Nicholas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903705/
https://www.ncbi.nlm.nih.gov/pubmed/36777188
http://dx.doi.org/10.1016/j.xgen.2022.100215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903705/
https://www.ncbi.nlm.nih.gov/pubmed/36777188
http://dx.doi.org/10.1016/j.xgen.2022.100215

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