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Oncogenic inspiration for programmable activators

The discovery of regulatory domains has been limited to the investigation of transcription factors and homologous protein sequences. In this issue of Cell Genomics, motivated by an oncogenic protein fusion, Tak et al.(1) direct the regulatory potential of a nontraditional effector domain to novel ge...

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Detalles Bibliográficos
Autores principales: Ichikawa, David, Noyes, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903755/
https://www.ncbi.nlm.nih.gov/pubmed/36776529
http://dx.doi.org/10.1016/j.xgen.2022.100122