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Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While many genes regulating embryonic development have been identified, the underlying CRE dynamics controlling their expression remain largely uncharacterized. T...

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Detalles Bibliográficos
Autores principales: McGarvey, Alison C., Kopp, Wolfgang, Vučićević, Dubravka, Mattonet, Kenny, Kempfer, Rieke, Hirsekorn, Antje, Bilić, Ilija, Gil, Marine, Trinks, Alexandra, Merks, Anne Margarete, Panáková, Daniela, Pombo, Ana, Akalin, Altuna, Junker, Jan Philipp, Stainier, Didier Y.R., Garfield, David, Ohler, Uwe, Lacadie, Scott Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903790/
https://www.ncbi.nlm.nih.gov/pubmed/36777038
http://dx.doi.org/10.1016/j.xgen.2021.100083