Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq

Hundreds of loci in human genomes have alleles that are methylated differentially according to their parent of origin. These imprinted loci generally show little variation across tissues, individuals, and populations. We show that such loci can be used to distinguish the maternal and paternal homolo...

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Detalles Bibliográficos
Autores principales: Akbari, Vahid, Hanlon, Vincent C.T., O’Neill, Kieran, Lefebvre, Louis, Schrader, Kasmintan A., Lansdorp, Peter M., Jones, Steven J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903809/
https://www.ncbi.nlm.nih.gov/pubmed/36777186
http://dx.doi.org/10.1016/j.xgen.2022.100233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903809/
https://www.ncbi.nlm.nih.gov/pubmed/36777186
http://dx.doi.org/10.1016/j.xgen.2022.100233

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