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A novel approach for large-scale manufacturing of small extracellular vesicles from bone marrow-derived mesenchymal stromal cells using a hollow fiber bioreactor

Mesenchymal stromal cells (MSCs) are promising therapeutic candidates in a variety of diseases due to having immunomodulatory and pro-regenerative properties. In recent years, MSC-derived small extracellular vesicles (sEVs) have attracted increasing interest as a possible alternative to conventional...

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Detalles Bibliográficos
Autores principales: Jakl, Viktoria, Ehmele, Melanie, Winkelmann, Martina, Ehrenberg, Simon, Eiseler, Tim, Friemert, Benedikt, Rojewski, Markus Thomas, Schrezenmeier, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904364/
https://www.ncbi.nlm.nih.gov/pubmed/36761296
http://dx.doi.org/10.3389/fbioe.2023.1107055