Targeting RNA G-quadruplex with repurposed drugs blocks SARS-CoV-2 entry

The rapid emergence of SARS-CoV-2 variants of concern, the complexity of infection, and the functional redundancy of host factors, underscore an urgent need for broad-spectrum antivirals against the continuous COVID-19 pandemic, with drug repurposing as a viable therapeutic strategy. Here we report...

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Detalles Bibliográficos
Autores principales: Tong, Qiyu, Liu, Geng, Sang, Xiongbo, Zhu, Xinyue, Fu, Xiaoli, Dou, Chao, Jian, Yue, Zhang, Jiani, Zou, Sailan, Zhang, Guixiang, Du, Xiao, Liu, Dan, Qi, Shiqian, Cheng, Wei, Tian, Yan, Fu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904497/
https://www.ncbi.nlm.nih.gov/pubmed/36701392
http://dx.doi.org/10.1371/journal.ppat.1011131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904497/
https://www.ncbi.nlm.nih.gov/pubmed/36701392
http://dx.doi.org/10.1371/journal.ppat.1011131

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