The mini-IDLE 3D biomimetic culture assay enables interrogation of mechanisms governing muscle stem cell quiescence and niche repopulation

Adult skeletal muscle harbours a population of muscle stem cells (MuSCs) that are required for repair after tissue injury. In youth, MuSCs return to a reversible state of cell-cycle arrest termed ‘quiescence’ after injury resolution. Conversely, some MuSCs in aged muscle remain semi-activated, causi...

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Detalles Bibliográficos
Autores principales: Jacques, Erik, Kuang, Yinni, Kann, Allison P, Le Grand, Fabien, Krauss, Robert S, Gilbert, Penney M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904761/
https://www.ncbi.nlm.nih.gov/pubmed/36537758
http://dx.doi.org/10.7554/eLife.81738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904761/
https://www.ncbi.nlm.nih.gov/pubmed/36537758
http://dx.doi.org/10.7554/eLife.81738

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