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Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast

The F-BAR protein Cdc15 is essential for cytokinesis in Schizosaccharomyces pombe and plays a key role in attaching the cytokinetic ring (CR) to the plasma membrane (PM). Cdc15’s abilities to bind to the membrane and oligomerize via its F-BAR domain are inhibited by phosphorylation of its intrinsica...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Rahul, Hall, Aaron R, Mangione, MariaSanta C, Igarashi, Maya G, Roberts-Galbraith, Rachel H, Chen, Jun-Song, Vavylonis, Dimitrios, Gould, Kathleen L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904764/
https://www.ncbi.nlm.nih.gov/pubmed/36749320
http://dx.doi.org/10.7554/eLife.83062