The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment

Endometriosis is a common inflammatory illness in which endometrial tissue grows outside the uterine cavity. Immune dysfunction is now widely acknowledged as the primary cause of endometriosis. The immune cell population represented by neutrophils is thought to play an essential role in the etiology...

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Autores principales: Wang, Xinlei, Jia, Yan, Li, Danyang, Guo, Xiaopin, Zhou, Zhengjie, Qi, Mingran, Wang, Guoqiang, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904898/
https://www.ncbi.nlm.nih.gov/pubmed/36762287
http://dx.doi.org/10.1155/2023/1481489
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author Wang, Xinlei
Jia, Yan
Li, Danyang
Guo, Xiaopin
Zhou, Zhengjie
Qi, Mingran
Wang, Guoqiang
Wang, Fang
author_facet Wang, Xinlei
Jia, Yan
Li, Danyang
Guo, Xiaopin
Zhou, Zhengjie
Qi, Mingran
Wang, Guoqiang
Wang, Fang
author_sort Wang, Xinlei
collection PubMed
description Endometriosis is a common inflammatory illness in which endometrial tissue grows outside the uterine cavity. Immune dysfunction is now widely acknowledged as the primary cause of endometriosis. The immune cell population represented by neutrophils is thought to play an essential role in the etiology, pathophysiology, and associated clinical outcome. There is growing evidence that neutrophils have a role in chronic and aseptic inflammatory diseases, and endometriosis patients have increased levels of neutrophils in plasma, peritoneal fluid, and ectopic endometrium. Here, we sought to review the function of neutrophils in the pathogenesis of endometriosis, with an emphasis on the role of neutrophils in regulating endometrial angiogenesis and the local inflammatory microenvironment.
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spelling pubmed-99048982023-02-08 The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment Wang, Xinlei Jia, Yan Li, Danyang Guo, Xiaopin Zhou, Zhengjie Qi, Mingran Wang, Guoqiang Wang, Fang Mediators Inflamm Review Article Endometriosis is a common inflammatory illness in which endometrial tissue grows outside the uterine cavity. Immune dysfunction is now widely acknowledged as the primary cause of endometriosis. The immune cell population represented by neutrophils is thought to play an essential role in the etiology, pathophysiology, and associated clinical outcome. There is growing evidence that neutrophils have a role in chronic and aseptic inflammatory diseases, and endometriosis patients have increased levels of neutrophils in plasma, peritoneal fluid, and ectopic endometrium. Here, we sought to review the function of neutrophils in the pathogenesis of endometriosis, with an emphasis on the role of neutrophils in regulating endometrial angiogenesis and the local inflammatory microenvironment. Hindawi 2023-01-31 /pmc/articles/PMC9904898/ /pubmed/36762287 http://dx.doi.org/10.1155/2023/1481489 Text en Copyright © 2023 Xinlei Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wang, Xinlei
Jia, Yan
Li, Danyang
Guo, Xiaopin
Zhou, Zhengjie
Qi, Mingran
Wang, Guoqiang
Wang, Fang
The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
title The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
title_full The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
title_fullStr The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
title_full_unstemmed The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
title_short The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
title_sort abundance and function of neutrophils in the endometriosis systemic and pelvic microenvironment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904898/
https://www.ncbi.nlm.nih.gov/pubmed/36762287
http://dx.doi.org/10.1155/2023/1481489
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