The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment
Endometriosis is a common inflammatory illness in which endometrial tissue grows outside the uterine cavity. Immune dysfunction is now widely acknowledged as the primary cause of endometriosis. The immune cell population represented by neutrophils is thought to play an essential role in the etiology...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904898/ https://www.ncbi.nlm.nih.gov/pubmed/36762287 http://dx.doi.org/10.1155/2023/1481489 |
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author | Wang, Xinlei Jia, Yan Li, Danyang Guo, Xiaopin Zhou, Zhengjie Qi, Mingran Wang, Guoqiang Wang, Fang |
author_facet | Wang, Xinlei Jia, Yan Li, Danyang Guo, Xiaopin Zhou, Zhengjie Qi, Mingran Wang, Guoqiang Wang, Fang |
author_sort | Wang, Xinlei |
collection | PubMed |
description | Endometriosis is a common inflammatory illness in which endometrial tissue grows outside the uterine cavity. Immune dysfunction is now widely acknowledged as the primary cause of endometriosis. The immune cell population represented by neutrophils is thought to play an essential role in the etiology, pathophysiology, and associated clinical outcome. There is growing evidence that neutrophils have a role in chronic and aseptic inflammatory diseases, and endometriosis patients have increased levels of neutrophils in plasma, peritoneal fluid, and ectopic endometrium. Here, we sought to review the function of neutrophils in the pathogenesis of endometriosis, with an emphasis on the role of neutrophils in regulating endometrial angiogenesis and the local inflammatory microenvironment. |
format | Online Article Text |
id | pubmed-9904898 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-99048982023-02-08 The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment Wang, Xinlei Jia, Yan Li, Danyang Guo, Xiaopin Zhou, Zhengjie Qi, Mingran Wang, Guoqiang Wang, Fang Mediators Inflamm Review Article Endometriosis is a common inflammatory illness in which endometrial tissue grows outside the uterine cavity. Immune dysfunction is now widely acknowledged as the primary cause of endometriosis. The immune cell population represented by neutrophils is thought to play an essential role in the etiology, pathophysiology, and associated clinical outcome. There is growing evidence that neutrophils have a role in chronic and aseptic inflammatory diseases, and endometriosis patients have increased levels of neutrophils in plasma, peritoneal fluid, and ectopic endometrium. Here, we sought to review the function of neutrophils in the pathogenesis of endometriosis, with an emphasis on the role of neutrophils in regulating endometrial angiogenesis and the local inflammatory microenvironment. Hindawi 2023-01-31 /pmc/articles/PMC9904898/ /pubmed/36762287 http://dx.doi.org/10.1155/2023/1481489 Text en Copyright © 2023 Xinlei Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Wang, Xinlei Jia, Yan Li, Danyang Guo, Xiaopin Zhou, Zhengjie Qi, Mingran Wang, Guoqiang Wang, Fang The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment |
title | The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment |
title_full | The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment |
title_fullStr | The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment |
title_full_unstemmed | The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment |
title_short | The Abundance and Function of Neutrophils in the Endometriosis Systemic and Pelvic Microenvironment |
title_sort | abundance and function of neutrophils in the endometriosis systemic and pelvic microenvironment |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904898/ https://www.ncbi.nlm.nih.gov/pubmed/36762287 http://dx.doi.org/10.1155/2023/1481489 |
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