The evaluation of in vitro antichagasic and anti-SARS-CoV-2 potential of inclusion complexes of β- and methyl-β-cyclodextrin with naphthoquinone

The compound 3a,10b-dihydro-1H-cyclopenta[b]naphtho[2,3-d]furan-5,10-dione (IVS320) is a naphthoquinone with antifungal and antichagasic potential, which however has low aqueous solubility. To increase bioavailability, inclusion complexes with β-cyclodextrin (βCD) and methyl-β-cyclodextrin (MβCD) we...

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Detalles Bibliográficos
Autores principales: Oliveira, Verônica da Silva, Silva, Cláudia Cândida, de Freitas Oliveira, Johny Wysllas, da Silva, Marcelo de Sousa, Ferreira, Patricia Garcia, da Siva, Fernando de Carvalho, Ferreira, Vitor Francisco, Barbosa, Euzébio Guimarães, Barbosa, Cecília Gomes, Moraes, Carolina Borsoi, Freitas-Junior, Lucio Holanda Gondim de, Converti, Attilio, Lima, Ádley Antonini Neves de
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905044/
https://www.ncbi.nlm.nih.gov/pubmed/36776572
http://dx.doi.org/10.1016/j.jddst.2023.104229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905044/
https://www.ncbi.nlm.nih.gov/pubmed/36776572
http://dx.doi.org/10.1016/j.jddst.2023.104229

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