Synthesis and biological evaluation of new β-D-N(4)-hydroxycytidine analogs against SARS-CoV-2, influenza viruses and DENV-2

Drug repurposing approach was applied to find a potent antiviral agent against RNA viruses such as SARS-CoV-2, influenza viruses and dengue virus with a concise strategy of small change in parent molecular structure. For this purpose, β-D-N(4)-hydroxycytidine (NHC, 1) with a broad spectrum of antivi...

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Detalles Bibliográficos
Autores principales: An, Yeon Jin, Choi, Se Myeong, Choi, Eun Rang, Nam, Ye Eun, Seo, Eun Woo, Ahn, Soo Bin, Jang, Yejin, Kim, Meehyein, Cho, Jong Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905048/
https://www.ncbi.nlm.nih.gov/pubmed/36764470
http://dx.doi.org/10.1016/j.bmcl.2023.129174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905048/
https://www.ncbi.nlm.nih.gov/pubmed/36764470
http://dx.doi.org/10.1016/j.bmcl.2023.129174

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