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Synthesis and biological evaluation of new β-D-N(4)-hydroxycytidine analogs against SARS-CoV-2, influenza viruses and DENV-2
Drug repurposing approach was applied to find a potent antiviral agent against RNA viruses such as SARS-CoV-2, influenza viruses and dengue virus with a concise strategy of small change in parent molecular structure. For this purpose, β-D-N(4)-hydroxycytidine (NHC, 1) with a broad spectrum of antivi...
Autores principales: | An, Yeon Jin, Choi, Se Myeong, Choi, Eun Rang, Nam, Ye Eun, Seo, Eun Woo, Ahn, Soo Bin, Jang, Yejin, Kim, Meehyein, Cho, Jong Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905048/ https://www.ncbi.nlm.nih.gov/pubmed/36764470 http://dx.doi.org/10.1016/j.bmcl.2023.129174 |
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