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Ghrelin signaling in the cerebellar cortex enhances GABAergic transmission onto Purkinje cells

Ghrelin, an orexigenic peptide ligand for growth hormone secretagogue receptor 1a (GHS-R1a), occurs not only in the stomach but also in the brain, and modulates neuronal activity and synaptic efficacy. Previous studies showed that GHS-R1a exists in the cerebellum, and ghrelin facilitates spontaneous...

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Detalles Bibliográficos
Autores principales: Hirono, Moritoshi, Nakata, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905081/
https://www.ncbi.nlm.nih.gov/pubmed/36750743
http://dx.doi.org/10.1038/s41598-023-29226-3