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The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice

Anti-CD19 chimeric antigen receptor (CAR) T cells represent a highly promising strategy for B-cell malignancies. Despite the inspiring initial achievement, remission in a notable fraction of subjects is short-lived, and relapse remains a major challenge. Tumor microenvironment (TME) was proved to be...

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Detalles Bibliográficos
Autores principales: Zhao, Kai, Ren, Chunxiao, Tang, Donghai, Zhao, Li, Chen, Xianxian, Wang, Ying, Xu, Kailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905118/
https://www.ncbi.nlm.nih.gov/pubmed/36761733
http://dx.doi.org/10.3389/fimmu.2023.1101769