Antitumor effects of lactate transport inhibition on esophageal adenocarcinoma cells

As a consequence of altered glucose metabolism, cancer cell intake is increased, producing large amounts of lactate which is pumped out the cytosol by monocarboxylate transporters (MCTs). MCT 1 and MCT4 are frequently overexpressed in tumors, and recently, MCT inhibition has been reported to exert a...

Descripción completa

Detalles Bibliográficos
Autores principales: Grasa, Laura, Chueca, Eduardo, Arechavaleta, Samantha, García-González, María Asunción, Sáenz, María Ángeles, Valero, Alberto, Hördnler, Carlos, Lanas, Ángel, Piazuelo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905156/
https://www.ncbi.nlm.nih.gov/pubmed/36342616
http://dx.doi.org/10.1007/s13105-022-00931-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905156/
https://www.ncbi.nlm.nih.gov/pubmed/36342616
http://dx.doi.org/10.1007/s13105-022-00931-3

Ejemplares similares