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Human antibodies targeting ENPP1 as candidate therapeutics for cancers

Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is a type II transmembrane glycoprotein expressed in many tissues. High expression levels of ENPP1 have been observed in many cancer types such as lung cancer, ovarian cancer, and breast cancer. Such overexpression has been associated with p...

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Detalles Bibliográficos
Autores principales: Chu, Xiaojie, Baek, Du-San, Li, Wei, Shyp, Taras, Mooney, Brian, Hines, Margaret G., Morin, Gregg B., Sorensen, Poul H., Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905232/
https://www.ncbi.nlm.nih.gov/pubmed/36761762
http://dx.doi.org/10.3389/fimmu.2023.1070492