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Construction of an efficient Claviceps paspali cell factory for lysergic acid production

Lysergic acid (LA) is the key precursor of ergot alkaloids, and its derivatives have been used extensively for the treatment of neurological disorders. However, the poor fermentation efficiency limited its industrial application. At the same time, the hardship of genetic manipulation has hindered th...

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Detalles Bibliográficos
Autores principales: Hu, Mingzhe, Zhou, Yu, Du, Siyu, Zhang, Xuan, Tang, Shen, Yang, Yong, Zhang, Wei, Chen, Shaoxin, Huang, Xuenian, Lu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905238/
https://www.ncbi.nlm.nih.gov/pubmed/36760750
http://dx.doi.org/10.3389/fbioe.2022.1093402