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Construction of an efficient Claviceps paspali cell factory for lysergic acid production
Lysergic acid (LA) is the key precursor of ergot alkaloids, and its derivatives have been used extensively for the treatment of neurological disorders. However, the poor fermentation efficiency limited its industrial application. At the same time, the hardship of genetic manipulation has hindered th...
Autores principales: | Hu, Mingzhe, Zhou, Yu, Du, Siyu, Zhang, Xuan, Tang, Shen, Yang, Yong, Zhang, Wei, Chen, Shaoxin, Huang, Xuenian, Lu, Xuefeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905238/ https://www.ncbi.nlm.nih.gov/pubmed/36760750 http://dx.doi.org/10.3389/fbioe.2022.1093402 |
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