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MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation

Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c) is a mitochondrial-derived peptide composed of 16 amino acids encoded by the 12S rRNA region of the mitochondrial genome. The MOTS-c protein is transferred to the nucleus during metabolic stress and directs the expression of nuclear genes to promote...

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Detalles Bibliográficos
Autores principales: Zheng, Yuejun, Wei, Zilin, Wang, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905433/
https://www.ncbi.nlm.nih.gov/pubmed/36761202
http://dx.doi.org/10.3389/fendo.2023.1120533