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HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop

Although dysregulated HMMR is linked to prostate cancer (PCa) prognosis, the precise mechanisms remain unclear. Here, we sought to elucidate the role of HMMR in PCa progression as well as underlying mechanism. Herein, we found that upregulation of HMMR frequently observed in PCa samples and was asso...

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Detalles Bibliográficos
Autores principales: Guo, Kaixuan, Liu, Cheng, Shi, Juanyi, Lai, Cong, Gao, Ze, Luo, Jiawen, Li, Zhuohang, Tang, Zhuang, Li, Kuiqing, Xu, Kewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905489/
https://www.ncbi.nlm.nih.gov/pubmed/36750558
http://dx.doi.org/10.1038/s41420-023-01341-0