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Solubility of palbociclib in supercritical carbon dioxide from experimental measurement and Peng–Robinson equation of state
Palbociclib is a poorly water-soluble medicine which acts against metastatic breast cancer cells. Among various techniques to improve the solubility of this medicine, applying supercritical technologies to produce micro- and nano-sized particles is a possible option. For this purpose, extraction of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905554/ https://www.ncbi.nlm.nih.gov/pubmed/36750582 http://dx.doi.org/10.1038/s41598-023-29228-1 |