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Solubility of palbociclib in supercritical carbon dioxide from experimental measurement and Peng–Robinson equation of state

Palbociclib is a poorly water-soluble medicine which acts against metastatic breast cancer cells. Among various techniques to improve the solubility of this medicine, applying supercritical technologies to produce micro- and nano-sized particles is a possible option. For this purpose, extraction of...

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Detalles Bibliográficos
Autores principales:	Sodeifian, Gholamhossein, Hsieh, Chieh-Ming, Tabibzadeh, Amirmuhammad, Wang, Hsu-Chen, Arbab Nooshabadi, Maryam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905554/ https://www.ncbi.nlm.nih.gov/pubmed/36750582 http://dx.doi.org/10.1038/s41598-023-29228-1

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