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RBM3 suppresses stemness remodeling of prostate cancer in bone microenvironment by modulating N6-methyladenosine on CTNNB1 mRNA

Bone metastasis is the most happened metastatic event in prostate cancer (PCa) and needs a large effort in treatment. When PCa metastasizes to the bone, the new microenvironment can induce the epigenome reprogramming and stemness remodeling of cancer cells, thereby increasing the adaptability of can...

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Detalles Bibliográficos
Autores principales: Zhang, Shouyi, Lv, Chengcheng, Niu, Yichen, Li, Changqi, Li, Xiuming, Shang, Yu, Zhang, Yunchao, Zhang, Yue, Zhang, Yong, Zeng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905585/
https://www.ncbi.nlm.nih.gov/pubmed/36750551
http://dx.doi.org/10.1038/s41419-023-05627-0