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Similarities and differences of chemical compositions and physical and functional properties of adjuvant system 01 and army liposome formulation with QS21

A vaccine adjuvant known as Adjuvant System 01 (AS01) consists of liposomes containing a mixture of natural congeners of monophosphoryl lipid A (MPL(®)) obtained from bacterial lipopolysaccharide, and a tree saponin known as QS21. Two vaccines containing AS01 as the adjuvant have been licensed, incl...

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Detalles Bibliográficos
Autores principales: Alving, Carl R., Rao, Mangala, Matyas, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905621/
https://www.ncbi.nlm.nih.gov/pubmed/36761767
http://dx.doi.org/10.3389/fimmu.2023.1102524