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Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine
INTRODUCTION: High intracellular concentrations of adenosine and 2’-deoxyadenosine have been suggested to be an important mediator of cell death. The aim of the present study was to characterize adenosine-induced death in insulin-producing beta-cells, at control and high glucose + palmitate-induced...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905624/ https://www.ncbi.nlm.nih.gov/pubmed/36761184 http://dx.doi.org/10.3389/fendo.2023.1060675 |