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Molecular mechanisms of the Guizhi decoction on osteoarthritis based on an integrated network pharmacology and RNA sequencing approach with experimental validation

Background: Our aim was to determine the potential pharmacological mechanisms of the Guizhi decoction (GZD) in the treatment of osteoarthritis (OA) through an integrated approach of network pharmacological analyses, RNA sequencing (RNA-seq), and experimental validation. Methods: The quality control...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Xue, Yan, Wang, Xuezong, Jiang, Ding, Xu, Qinguang, Wang, Lin, Zheng, Yuxin, Shi, Ying, Cao, Yuelong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905689/
https://www.ncbi.nlm.nih.gov/pubmed/36760992
http://dx.doi.org/10.3389/fgene.2023.1079631