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Atlantic cod (Gadus morhua) MHC I localizes to endolysosomal compartments independently of cytosolic sorting signals

Major histocompatibility complex (MHC) class I and II are crucial for the adaptive immune system because they are involved in peptide presentation to T cells. Until recently, it was believed that MHC genes and their associated immune components had been conserved since their evolutionary emergence i...

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Detalles Bibliográficos
Autores principales: Bjørnestad, Synne Arstad, Solbakken, Monica Hongrø, Jakobsen, Kjetill S., Jentoft, Sissel, Bakke, Oddmund, Progida, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905690/
https://www.ncbi.nlm.nih.gov/pubmed/36760361
http://dx.doi.org/10.3389/fcell.2023.1050323