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Chromosome conformation capture approaches to investigate 3D genome architecture in Ankylosing Spondylitis

Ankylosing Spondylitis (AS) is a chronic inflammatory arthritis of the spine exhibiting a strong genetic background. The mechanistic and functional understanding of the AS-associated genomic loci, identified with Genome Wide Association Studies (GWAS), remains challenging. Chromosome conformation ca...

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Detalles Bibliográficos
Autores principales: Davidson, Connor, Wordsworth, B. Paul, Cohen, Carla J., Knight, Julian C., Vecellio, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905691/
https://www.ncbi.nlm.nih.gov/pubmed/36760998
http://dx.doi.org/10.3389/fgene.2023.1129207