Synthetic lethal interactions of DEAD/H-box helicases as targets for cancer therapy

DEAD/H-box helicases are implicated in virtually every aspect of RNA metabolism, including transcription, pre-mRNA splicing, ribosomes biogenesis, nuclear export, translation initiation, RNA degradation, and mRNA editing. Most of these helicases are upregulated in various cancers and mutations in so...

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Detalles Bibliográficos
Autores principales: Arna, Ananna Bhadra, Patel, Hardikkumar, Singh, Ravi Shankar, Vizeacoumar, Frederick S., Kusalik, Anthony, Freywald, Andrew, Vizeacoumar, Franco J., Wu, Yuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905851/
https://www.ncbi.nlm.nih.gov/pubmed/36761420
http://dx.doi.org/10.3389/fonc.2022.1087989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9905851/
https://www.ncbi.nlm.nih.gov/pubmed/36761420
http://dx.doi.org/10.3389/fonc.2022.1087989

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